Further Reading: Fundamental of Enzyme Catalysis
The following three articles (and introduction) were published in
the "minireview" series of the Journal of Biological
Chemistry. They give a flavor for the current level of debate
and controversy surrounding our understanding (or lack thereof) of
how enzymes work.
Introduction (pdf)
Enzyme catalysis in terms of
electrostatics (pdf)
Enzyme catalysis in terms of stong
hydrogen bonds (pdf)
Enzyme catalysis in terms of solvent
effects (pdf)
In addition, the papers listed
here may be of interest.
